Some of the autistic children born to mothers who took thalidomide also had misshapen ears, as well as abnormalities in the nerves of the head and face.
The patient was treated with thalidomide 400 mg daily for 10 weeks.
Most folks who know about drug discovery will tell you about the lessons of thalidomide as they relate to the chirality of drugs.
Cases of phocomelia in the early 1960's in Germany and Australia led to the identification of thalidomide as a human teratogen.
Kevin is one of the many people born with shortened limbs after his mother took thalidomide to treat morning sickness during pregnancy.
Studies have shown that administration of thalidomide improves weight gain in both HIV-positive and HIV-negative tuberculosis patients.
Virtually all patients who have received thalidomide over the past six years have received the drug for cancer, making this drug the only one in the country whose use is exclusively off label.
Between 1957 and the early 1960s, thalidomide was used by several thousand pregnant women across the world to ease their morning sickness.
However, between May and October, a doctor in Australia discovered that the common factor in a number of monster births was that the mothers had taken thalidomide during pregnancy.
This was in spite of such FDA victories as the ban of thalidomide , which caused phocomelia in more than 8000 babies in Europe, where the drug was freely used.