Finally, we determined whether PPAR [gamma] activation increased CD36 expression by human AMs, and consequently augmented their phagocytic capacity for apoptotic neutrophils.
Clearance of apoptotic cells by phagocytes is crucial in maintaining tissue homeostasis.
Neutrophils and monocytes are the most phagocytic of the white blood cells; they ingest foreign particles, bacteria, and degenerating cells and cell fragments whether or not they can digest them.
Fc receptors mediate various effects on immune cells, including proliferation of B cells and phagocytosis by phagocytes .
Histologic studies have shown polymetric birefringent particles surrounded by mononuclear phagocytes and multinucleated foreign body giant cells.
Endothelial cells and mononuclear phagocytes are likely cellular mediators of lung IRI.
Neupogen can enhance the phagocytic activities of neutrophilic leukocytes; including activity directed at autologous platelets.
Products of complement activation cause smooth muscle contraction and increased vascular permeability and induce degranulation of phagocytic cells, mast cells, and basophils.
We hypothesized that AMs may be the primary cells responding to CpG motifs, because they are situated at the first-line defense in the lower respiratory tract with potent phagocytic capacity.
Following IVIG therapy in patients with ITP, platelet counts generally rise, apparently by Fc receptor blockade of splenic phagocytes and other reticuloendothelial cells.