Increased hypoxia in local tissues, marked oedema of the toes, or development of venous hypertension may be involved.
This is not easy, as too little fluid will cause hypoperfusion whereas too much will lead to oedema that will cause tissue hypoxia .
The hypothetical role of tissue hypoxia also needs to be explored.
Oxygen is cheap, widely available, and used in a range of settings and conditions to relieve or prevent tissue hypoxia .
Emersion results in hypoxia in many aquatic crustaceans.
These hemorrhagic and hemolytic events would result in tissue hypoxia that would, in turn, stimulate erythropoiesis.
Seizures are usually due to hypoxic encephalopathy, hemorrhage or cerebral infarction.
Control tissues were free of significant autolysis and showed no signs of hypoxic or ischemic injury.